Sample size calculations: basic principles and common pitfalls
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چکیده
منابع مشابه
CME Series Sample size calculations: basic principles and common pitfalls
One of the most common requests that statisticians get from investigators are sample size calculations or sample size justifications. The sample size is the number of patients or other experimental units included in a study, and determining the sample size required to answer the research question is one of the first steps in designing a study. Although most statistical textbooks describe techni...
متن کاملSample size calculations: basic principles and common pitfalls.
One of the most common requests that statisticians get from investigators are sample size calculations or sample size justifications. The sample size is the number of patients or other experimental units included in a study, and determining the sample size required to answer the research question is one of the first steps in designing a study. Although most statistical textbooks describe techni...
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Addressing a sample size is a practical issue that has to be solved during planning and designing stage of the study. The aim of any clinical research is to detect the actual difference between two groups (power) and to provide an estimate of the difference with a reasonable accuracy (precision). Hence, researchers should do a priori estimate of sample size well ahead, before conducting the stu...
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T he analysis of clinical samples, population samples, and controlled trials is typically subjected to rigorous statistical review. This fact is understandable, given that the results of clinical investigation will often be used to inform patient care or clinical decision making. One would not want to predicate patient advice on research findings that are not correctly interpreted or valid. For...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2010
ISSN: 0931-0509,1460-2385
DOI: 10.1093/ndt/gfq563